I am broadly interested in evolutionary ecology, particularly how the environment and developmental processes affect evolution. Different forms of phenotypic plasticity are therefore reoccurring in my work. My previous work focused mainly on how genes affect (social) behavior and the other way around. I am now broadening my scope into the exciting fields of developmental plasticity and epigenetics. I am rounding-up a project on maternal effects in Daphnia and start to work on the importance of developmental bias in evolution.
The relative importance of development bias in evolution
developmental bias - genetics - epigenetics
In the traditional framework of evolution, mutations are regarded as the ultimate source of genetic variation and natural selection as the filtering process determining which variants are conserved for future generations and which are not. Effects of the environment as well as developmental processes on the way genotypes translate to phenotypes are regarded random and not affecting evolution. However, the developmental system organisms are subject to is also shaped by evolution, therefore the way genes and the environment affect the phenotype are coordinated and can be directional and even functional. The evolutionary trajectory a species takes is therefore affected by development. This developmental bias is often marginalized as anecdotal. In this project we will use meta-analysis to investigate how widespread developmental bias is, whether cryptic genetic variation — which is released in novel environments — is non-random and how phenotypic plasticity plays a role in these processes. This project is part of the Extended Evolutionary Synthesis research program.
Uller T, Feiner N, Radersma R, Jackson I, Rago A, 2019. Developmental plasticity and evolutionary explanations. Evolution & Development. : e12314.
Noble DWA*, Radersma R*, Uller T, 2019. Plastic responses to novel environments are biased towards phenotype dimensions with high additive genetic variation. Proceedings of the National Academy of Sciences of the United States of America. 116: 13452-13461.
Bayesian methods in ecology and evolution
social networks - genetics - epigenetics
The amounts of genomic and phenotypic data collected in ecology and evolution are surging. The collection of more and new types of data require new analytical techniques; generalized linear mixed models do not always offer the right tools and therefore more flexibility is needed. Among other benefits, Bayesian statistical techniques offer tremendous flexibility of model structure and the integration of uncertainty. I use Stan, a general-purpose Bayesian inference library and language, which utilizes novel algorithms to efficiently deal with highly dependent data structures. I develop and use novel model structures to analyze high dimensional dependent data structures to for instance infer extra-genetic or indirect genetic effects.
4/2018: Presentation. Inference in ecology and evolution beyond generalised linear mixed models. Presentation at Bayes@Lund 2018 conference. Presentation at a conference on applied Bayesian statistics, for researchers and professionals of all disiplines working with or interested in Bayesian methods.
The transgenerational tolerance of Daphnias to cyanobacteria
epigenetics - life history
When exposed to cyanobacteria, daphnids are known to build up resistance to microcystin — a toxin produced by cyanobacteria — over (clonal) generations. This could be a positive maternal effect in which mothers prepare their offspring to the environment they will encounter, by for instance adding particular proteins to the eggs. However, a toxic environment also affects the growth of mothers, which ultimately affects the amount of resources they can provide to their offspring and therefore the offspringâs fitness. In this project we investigate the interplay between those two (positive and negative) maternal effects. We investigate the effect of different levels of toxicity on different genotypes and life phases. As part of this project we also test whether DNA methylation can act as a mechanism of inheritance for this resistance to microcystin.
Radersma R, Hegg A, Noble DWA, Uller T, 2018. Timing of maternal exposure to toxic cyanobacteria and offspring fitness in Daphnia magna: implications for the evolution of anticipatory maternal effects. Ecology and Evolution. 8: 12727-12736.
Paredes U, Radersma R, Cannell N, While GM, Uller T, 2016. Low Incubation Temperature Induces DNA Hypomethylation in Lizard Brains. Journal of Experimental Zoology Part A: Ecological Genetics and Physiology. 325: 390-395.
The interplay between genes and social structure
genetics - social networks - life history
Currently I am working on genetics and social structure in tit species. A particular dynamic relationship is present between genes and social structure, because gene flow is strongly influenced by the social structure of a species while genes have the ability to dictate social behaviour. We collect data on the social structure of various passerines (Great tits, Blue tits, Marsh tits and Nuthatches) by registering visits to feeding stations at the individual level with radio frequency identification tags. We translate the social structure into social networks to quantify "social phenotypes". For Great tits a SNP-chip was developed and for two years most breeding pairs were genotyped. We also have pedigree data for both Great tits and Blue tits, which enables us to use "animal models" to infer genetic effects. Combining the social network data and the genotypes enables us to address questions regarding genetics and social structure. I focus on investigating the effect of social behaviour on the spatial distribution of genotypes, mate choice and genetics, quantitative genetics (both pedigree and marker based) of social behaviour and the evolutionary consequences of social behaviour. This project is part of a large project on the role of social processes in evolutionary ecology funded by an ERC grant awarded to Prof Ben Sheldon.
Radersma R, Garroway CJ, Santure AW, De Cauwer I, Farine DR, Slate S, Sheldon BC, 2017. Social and spatial effects on genetic variation between foraging flocks in a wild bird population. Molecular Ecology. 26: 5807-5819.
Kasper C, Vierbuchen M, Ernst U, Fischer S, Radersma R, Raulo A, Cunha-Saraiva F, Wu M, Mobley K, Taborsky B, 2017. Genetics and developmental biology of cooperation. Molecular Ecology. 26: 4364-4377.
Milligan ND, Radersma R, Cole EF, Sheldon BC, 2017. To graze or gorge: consistency and flexibility of individual foraging tactics in tits. Journal of Animal Ecology. 86: 826-836.
Crates RA, Firth JA, Farine DR, Garroway CJ, Kidd LR, Aplin LM, Radersma R, Milligan ND, Voelkl B, Culina A, Verhelst BL, Hinde CA, Sheldon BC, 2016. Individual variation in winter supplementary food consumption and its consequences for reproduction in wild birds. Journal of Avian Biology. 47: 678-689.
Aplin LM, Firth JA, Farine DR, Voelkl B, Crates RA, Culina A, Garroway CJ, Hinde CA, Kidd LR, Psorakis I, Milligan ND, Radersma R, Verhelst BL, Sheldon BC, 2015. Consistent individual differences in the social phenotypes of wild great tits, Parus major. Animal Behaviour. 108: 117-127.
Farine DR, Firth JA, Aplin LM, Crates RA, Culina A, Garroway CJ, Hinde CA, Kidd LR, Milligan ND, Psorakis I, Radersma R, Verhelst B, Voelkl B, Sheldon BC, 2015. The role of social and ecological processes in structuring animal populations: a case study from automated tracking of wild birds. Royal Society Open Science. 2: 150057.
Radersma R, Sheldon BC, 2015. A new permutation technique to explore and control for spatial autocorrelation. Methods in Ecology and Evolution. 6: 1026-1033.
Psorakis I, Voelkl B, Garroway CJ, Radersma R, Aplin LM, Crates RA, Culina A, Farine DR, Firth JA, Hinde CA, Kidd LR, Milligan ND, Roberts SJ, Verhelst B, Sheldon BC, 2015. Inferring social structure from temporal data. Behavioral Ecology and Sociobiology. 69: 857-866.
Sepil I, Radersma R, Santure AW, De Cauwer I, Slate J, Sheldon BC, 2015. No evidence for MHC class I based disassortative mating in a wild population of great tits. Journal of Evolutionary Biology. 28: 643-654.
Garroway CJ, Radersma R, Hinde CA, 2014. Perspectives on social network analyses of bird populations. In: Animal social networks (eds: Krause J, James R, Franks D and Croft DP). Oxford University Press: 171-183.
Garroway CJ*, Radersma R*, Sepil I, Santure AW, De Cauwer I, Slate J, Sheldon BC, 2013. Fine-scale genetic structure in a wild bird population: the role of limited dispersal and environmentally-based selection as causal factors. Evolution. 67: 3488-3500.
The ecological and evolutionary consequences of brood sex ratio variation
sex allocation - life history
Sex allocation theory is successful in predicting sex ratio variation in some taxa, but often not in birds and mammals. An important reason may be that most theoretical models do not account for the complexities of avian and mammalian life-history. To reveal the adaptive significance of sex allocation to avian life-history, I conducted an experimental study on great tits (Parus major). I investigated the effect of manipulated brood sex ratios on long-term fitness benefits. Offspring that was raised in broods with sex ratios at parity had the highest fecundity. Since offspring recruitment, parental survival and parental future fecundity were unaffected, there was stabilizing selection for producing brood sex ratios at parity. To gain insight in the underlying mechanism I focused on different aspects of the offspringï¿½s first year. Brood sex ratio did not affect fledging behaviour, but there were some effects on social behaviour in winter, which did not correlate to fitness. As adults, individuals raised as the rare sex in a brood had larger tarsi than individuals of the abundant sex. This relationship was neither present in the nestling phase nor caused by selective disappearance. This suggests a sex-specific directional effect of brood sex ratio on the late development of the offspring, which potentially links brood sex ratio to fecundity. Stabilizing selection for brood sex ratios at parity might provide an explanation why sex allocation in birds and mammals is often subtle. Higher benefits for equal brood sex ratios counteract selection for facultative sex allocation to extreme values.
Michler SPM, Nicolaus M, Van der Velde M, Radersma R, Ubels R, Both C, Komdeur J, Tinbergen JM, 2013. Local offspring density and sex ratio affect sex allocation in the great tit. Behavioral Ecology. 24 (1): 169-181.
12/2012: Printed press. Gemengd gezin doet het goed. Article in ExperimentNL. Annual publication by The Netherlands Organisation for Scientific Research (NWO) and Quest (popular science magazine, in Dutch).
11/12/2011: Radio. News item at VARA Vroege Vogels. Weekly program about nature and environment (national radio, in Dutch).
9/12/2011: Internet. Family composition determines success of great tit parents. Article on Phys.org. International science, research and technology news website.
6/12/2011: Printed press. Gezinssamenstelling bepaalt succes van koolmees-ouders. Article in Trouw. National daily newspaper (in Dutch).
3/2011: Printed press. Kiezen voor meer zonen of dochters? Article in De Levende Natuur. Professional journal for nature conservation and management in the Netherlands and Flanders (in Dutch).
fledging - life history
One of the most dramatic changes a cavity nesting bird will ever experience in life is leaving the safety of the nest it was born in and start exploring the outside world. In this project we try to understand of the social dynamics around this moment called fledgling.
Radersma R, Komdeur J, Tinbergen JM, 2015. Early morning fledging improves recruitment in Great Tits Parus major. Ibis. 157: 351-355.
Radersma R, Tinbergen JM, Komdeur J, 2011. Do brood sex ratio, nestling development and sex affect fledging timing and order? An experimental study on great tits. Animal Behaviour. 81 (1): 69-75.
Winter ecology of Bewick's swans
foraging ecology - life history - epidemics
Bewick's swans (Cygnus columbianus bewickii) breed in Siberia and winter in Western Europe. Visiting crowed areas like the Netherlands result in conflicts between Bewick's swans and humans, because of for instance foraging on agricultural lands and the potential spread of avian influenza. In this project we investigated space use and foraging in winter by the Bewick's swans. We equipped 12 Bewick's swans with GPS-loggers to track then throughout the winter. We related their movements to both their infection status of a low-pathogenic avian influenza and to vegetation quality and growth.
Van Gils JA, Munster VJ, Radersma R, Liefhebber D, Fouchier RAM, Klaassen M, 2007. Hampered foraging and migratory performance in swans infected with low-pathogenic avian influenza A virus. PLoS ONE. 2(1): e184.